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Solid phase extraction (SPE) is a popular pretreatment method for purifying liquid samples with solid sorbents. Normally, SPE is used before chromatography or other analysis for sample purification, concentration, desalination, derivation or isolation.
The function of SPE and LLE (liquid/liquid extraction) is similar. LLE is the extraction of two immiscible liquid phases, while SPE is the extraction from liquid phase to solid phase. T